The installation of the organ was reported in the Carlisle (PA) Herald, April 8, 1857:

New Church Organ.—A new and
splendid organ, of twelve stops, from the well
known manufactory of Mr. Pomplitz, of Balti-
more, has been erected in the gallery of the
First Presbyterian Church in Carlisle. Our
musical critic happens to be absent just now,
and we cannot venture to speak particularly
and descriptively of such an affair as an organ
but of the vast crowd who heard its performan-
ces on Sunday last, we believe the universal
opinion is that it combines in the highest
degree sweetness and softness of tone with
great power. It is a well finished instrument
and presents an attractive appearance. We
congratulate the congregation on the pos-
session of such an auxiliary to their church
music.

In view of the 1857 date, the "manufactory of Mr. Pomplitz" was most likely Pomplitz & Rodewald.

Source:

"Town and County Matters" (column), Carlisle (PA) Herald, April 8, 1857, 2, Newspapers.com, accessed January 1, 2022, https://www.newspapers.com/image/270317059/.

Replaced by C.S. Haskell in 1892. Known from an article in The Sentinel (Carlisle, Pennsylvania) · 3 Nov 1892, Thu · Page 3. "The former organ had done duty for about 40 years and no longer met the requirement." Also the article reported that one woman was present at the Haskell dedication who also "attended the dedication of the previous organ 40 years ago."